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第二军医大学学报Academic Journal of Second Military Medical University
2001 Vol.22 No.1 P.80-82
妊娠合并甲状腺功能亢进症40例的诊断和处理
徐明娟 沙金燕 孔令山
摘 要：目的：探讨妊娠合并甲状腺功能亢进症(甲亢)的诊断、治疗及新生儿结局。方法：产前测定合并甲亢孕妇外周血甲状腺激素［三碘四腺原氨酸(T3)和甲状腺素(T4)］、促甲状腺素(TSH)水平的变化，了解分娩方式及新生儿结局；通过抽脐血查T3、T4、TSH以了解新生儿甲状腺功能。结果：甲亢未治疗组甲状腺激素T3、T4、游离T4(FT4)、游离T3(FT3)水平明显高于治疗组和对照组(P<0.01),治疗组甲状腺激素水平控制在正常上限或增高20%以内。甲亢组分娩绝大多数为难产（P<0.05），占90%。未治疗组新生儿体质量明显低于治疗组和对照组(P<0.01)，且有1例新生儿甲亢出现。结论：甲亢应早期诊断和治疗，病情缓解后受孕对新生儿无明显影响。
关键词：妊娠并发症；甲状腺功能亢进
文章编号：0258-879X(2001)01-0080-03
Diagnosis and treatment of
40 cases of hyperthyroidism in pregnancy
XU Ming-Juan（Department of Obstetrics and Gynecology, Changhai
Hospital, Second Military Medical University, Shanghai 200433, China）
SHA Jin-Yan（Department of Obstetrics and Gynecology, Changhai
Hospital, Second Military Medical University, Shanghai 200433, China）
KONG Ling-Shan（Department of Nuclear Medicine）
Abstract：Objective: To study the
diagnosis， treatment
and outcome of infants in patients with hyperthyroidism in pregnancy. Methods: The levels
of T3，T4，TSH，FT3，FT4 in 40 cases of hyperthyroid gravida and
control group were measured before delivery, the route of delivery and the outcome of
infants were studied, and the neonatal thyroid functions were evaluated by the levels of T3，T4，TSH in cord serum samples .
Results: The levels of T3，T4，FT3，FT4 in non-treatment group were higher than that of
treatment group and control(P<0.01); an increased rate of forceps and cesarean in
hyperthyroid gravida was seen compared with that in control group, about 90%(36/40); the
body weights of infants in non-treatment group were lower than that in treatment and
control group. There was a case of neonatal hyperthyroidism in non-treatment group.
Conclusion : Hyperthyroidism should be diagnosed and treated earlier and there is little
side effects on the outcome of infants.
Keywords：pregnancy complication; hyperthyroidism
作者简介：徐明娟(1968-),女(汉族),硕士,主治医师
E-mail:dwaou@smmu.edu cn.
作者单位：徐明娟（第二军医大学长海医院妇产科，上海200433）
沙金燕（第二军医大学长海医院妇产科，上海200433）
孔令山（核医学科） 参考文献：
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