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听力学及言语疾病杂志JOURNAL OF AUDIOLOGY AND SPEECH PATHOLOGY
2003 Vol.11 No.4 P.241-242
关于听神经病之我见
李兴启
孙�
文章编号：1006-7299(2003)04-0241-02
关于听神经病的定义,现在国内外学者有了较为一致的看法,即临床表现为不同程度的听力损失,听功能检查示诱发性耳声发射(evoked otoacoustic emission,EOAE)正常、而听性脑干反应(auditory brainstem response,ABR)缺失或严重异常的疾病[1].其突出的临床特点为比纯音听阈下降更为严重的言语分辨率的损害[2].关于听神经病的病变部位和发病机制还需要进一步探讨.……
作者单位：李兴启（解放军总医院耳鼻咽喉科研究所,北京,100853）
孙�（解放军总医院耳鼻咽喉科研究所,北京,100853）
参考文献：
［1］Starr A, Picton TW, Sininger Y, et al. Auditory neuropathy[J].Brain, 1996, 119:741.
［2］Brown DK, Dort JC. Auditory Neuropathy: when test results conflict[J]. J otolaryngol,2001,30:46.
［3］顾瑞,于黎明.中枢性低频感音神经性听力减退[J].中华耳鼻咽喉科杂志,1992,1:27.
［4］Miyamoto RT, Kirk KI, Renshaw J. Cochlear Implantation in Auditory Neuropathy[J]. Laryngoscope, 1999, 109: 181.
［5］Buss E, Labadie RF, Brown CJ, et al. Outcome of Cochlear Implantation in Pediatric Auditory Neuropathy[ J]. Oto - Neurotology, 2002,3:328.
［6］Sawada S, Mori N, Mount R J, et al. Differential Vulnerability of Inner and Outer Hair Cell Systems to Chronic Mild Hypoxia and Glutamate Ototoxicity: Insights into the Cause of Auditory Neuropathy[ J]. J otolaryngol, 2001,30:106.
［7］Puel JL. Chemical synaptic transmission in the cochlear[J]. ProgNeurobiol, 1995, 4:449.
［8］Shapiro SM, Nakamura H. Bilirubin and the auditory system[ J ]. J perinatol, 2001,21 ( suppll ): s52.
［9］Butinar D, Starr A, Vatovec J. Brainstem auditory evoked potentials and cochlear microphonics in the HMAN family with AN[J]. P flugers Arch,2000, 439: R204.
［10］Sawada M. Electrocochleography of ears with mumps deafness [ J ].Arch Otol, 1979, 105:475.
［11］Lesinski- Schiedat A, Frohne C, Hemmaouil I, et al. Subjective deafness in case of peri - synaptic audiopathy. Isolated defects of the inner haircells[J]? Laryngorhinootologie,2001,80: 601.
［12］Sakaguchi H. Electrocochleography in deaf subjects[J]. J Oto - Rhino - Laryngology, 1994, 56:133.
［13］Ottersen OP, Takumi Y, Matsubara A, et al. Molecular organization of a type of peripheral glutamate synapse: the afferent synapses of hair cells in the inner ear[J]. Prog in neurobiology, 1998,54:127.
［14］Li XQ, Sun JH, Yu N, et al. Glutamate induced modulation of free Ca2 + in isolated inner hair cells of the guinea pig cochlea[ J ]. Hear Res, 2001, 161:29.
［15］Hood LJ. A review of objective methods of evaluating auditory neural pathways[J]. Laryngoscope, 1999,109:1 745.
［16］Li XQ, Sun JH, Sun W, et al. Changes of summating potentials and morphology in the guinea pig cochlea during anoxia[ J]. Chinese J of Acoustics, 1995, 14:358